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Federal University Oye-Ekiti Institutional Repository >
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Please use this identifier to cite or link to this item:
http://repository.fuoye.edu.ng/handle/123456789/1357
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| Title: | PROPHYLACTIC ACTIVITY OF Diodia scandens CRUDE EXTRACTS ON SWISS ALBINO RATS |
| Authors: | OLOWOKERE, VICTORIA BUKOLA
OJO, S.K.S |
| Keywords: | PROPHYLACTIC ACTIVITY
Diodia scandens
CRUDE EXTRACTS
SWISS ALBINO RATS |
| Issue Date: | Oct-2015 |
| Publisher: | FEDERAL UNIVERSITY OYE EKITI |
| Series/Report no.: | DEPARTMENT OF MICROBIOLOGY THESIS;MCB/11/0344 |
| Abstract: | The aim of this study was to evaluate the prophylactic activity of Diodia scandens on
Swiss albino rats challenged with Staphylococcus epidermidis. Twenty (20) Swiss albino
rats of both sexes weighing (120-200) were housed in polycarbonated cages at ambient
environmental condition of 23±2oC, 30-60% relative humidity. They were defasted for
4hour prior to treatment. Different concentrations of different extracts (50mg/kg and
100mg/kg) of Diodia scandens were given according to the weight of rats and were
challenged with 0.5ml of 1×108 cfu/ml of Staphylococcus epidermidis in Mueller Hinton
broth using 0.5 Mcfarland standards at the 4th day of the pre-treatment. The result
showed aggressiveness, no fever or inflammation during the pre-treatment. After the
organism challenge test it was observed that with some level of protection were offered
by extract of Diodia scandens on the rats. |
| Description: | The protection offered by Diodia scandens
after organism challenged test has shown that the plant is potent, effective and had
boosted the immunity of the rats against Staphylococcus epidermidis. It was concluded
that 50mg/kg and 100mg/kg of Diodia scandens was effective during pre-treatment and
was not toxic on the rats. |
| URI: | http://repository.fuoye.edu.ng/handle/123456789/1357 |
| ISSN: | MCB/11/0344 |
| Appears in Collections: | Microbiology Thesis
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